Ubiquitin-Conjugating Enzyme E2 L3 (UBE2L3) Antibody
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Catalogue No: abx031525
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.
Research Articles on Ubiquitin-Conjugating Enzyme E2 L3 (UBE2L3)
| Target | Ubiquitin-Conjugating Enzyme E2 L3 (UBE2L3) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P68036 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R4A7, B4DDG1, B4DSZ4, E7EWS7, P51966, P70653, Q9HAV1 |
| UniProt Entry Name | UB2L3_HUMAN |
| NCBI Accession | NP_001243284.1 NP_001243285.1 NP_003338.1 |
| KEGG | hsa:7332 |
| String | 9606.ENSP00000485133 |
| Molecular Weight | Calculated MW: 17.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow UBE2L3. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |