Ubiquitin-Protein Ligase E3C (UBE3C) Antibody
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Catalogue No: abx034815
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US$326.25
(Size: 80 µl)
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Datasheet SDS
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'-or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
Research Articles on Ubiquitin-Protein Ligase E3C (UBE3C)
| Target | Ubiquitin-Protein Ligase E3C (UBE3C) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 549-578 amino acids from the Central region of human UBE3C. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q15386 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D235, A6NCP3, Q8TC15, Q96CR4, Q9UDU3 |
| UniProt Entry Name | UBE3C_HUMAN |
| NCBI Accession | NP_055486.2 |
| KEGG | hsa:9690 |
| String | 9606.ENSP00000309198 |
| Molecular Weight | Calculated MW: 124 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |