WAP Four Disulfide Core Domain Protein 1 (WFDC1) Antibody
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Catalogue No: abx026836
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.
Research Articles on WAP Four Disulfide Core Domain Protein 1 (WFDC1)
| Target | WAP Four Disulfide Core Domain Protein 1 (WFDC1) |
| Research Area | Signal Transduction, Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 148-177 amino acids from the C-terminal region of human WFDC1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9HC57 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DUL7, Q8NC27, Q9HAU1 |
| UniProt Entry Name | WFDC1_HUMAN |
| Gene Symbol | WFDC1 |
| String | 9606.ENSP00000219454 |
| Molecular Weight | Calculated MW: 24 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |