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E3 Ubiquitin-Protein Ligase XIAP (XIAP) Antibody
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Catalogue No: abx032692
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US$326.25
(Size: 80 µl)
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Datasheet SDS
BIRC4 is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.
Research Articles on E3 Ubiquitin-Protein Ligase XIAP (XIAP)
| Target | E3 Ubiquitin-Protein Ligase XIAP (XIAP) |
| Research Area | Apoptosis |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human XIAP (BIRC4). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P98170 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DTF2, Q9NQ14 |
| UniProt Entry Name | XIAP_HUMAN |
| KEGG | hsa:331 |
| String | 9606.ENSP00000360242 |
| Molecular Weight | Calculated MW: 56.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |