Abelson Tyrosine-Protein Kinase 2 (ABL2) Antibody

ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. The peptide used to generate this antibody is 100% conserved between ABL2 and ABL1.

Target	Abelson Tyrosine-Protein Kinase 2 (ABL2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 417-446 amino acids from human ABL2.
Isotype	IgG
Form	Liquid
Purification	Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified. The antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P42684 (UniProt, ExPASy)
UniProt Entry Name	ABL2_HUMAN
Gene Symbol	ABL2
KEGG	hsa:27
String	9606.ENSP00000427562
Enzyme Commission Number	EC 2.7.10.2
Molecular Weight	Calculated MW: 128 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Zebrafish ABL2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Abelson Tyrosine-Protein Kinase 2 (ABL2)

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