B-Raf Proto Oncogene Serine/Threonine Protein Kinase Phospho-Ser601 (BRAF pS601) Antibody

This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product.

This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product.

BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.

Target	B-Raf Proto Oncogene Serine/Threonine Protein Kinase Phospho-Ser601 (BRAF pS601)
Clonality	Polyclonal
Target Modification	Ser601
Modification	Phosphorylation
Reactivity	Human
Tested Applications	ELISA, DB
Host	Rabbit
Recommended dilutions	DB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S601 of human BRAF.
Isotype	IgG
Form	Liquid
Purification	Purified by protein A affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with peptides. The antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P15056 (UniProt, ExPASy)
UniProt Entry Name	BRAF_HUMAN
KEGG	hsa:673
String	9606.ENSP00000288602
Molecular Weight	Calculated MW: 84.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Chicken BRAF.
Availability	Please enquire.
Note	This product is for research use only.

Research Articles on B-Raf Proto Oncogene Serine/Threonine Protein Kinase Phospho-Ser601 (BRAF pS601)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue