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C-C Chemokine Receptor Type 7 (CCR7) Antibody
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Catalogue No: abx032372
Price:
US$326.25
(Size: 80 µl)
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CCR7 is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.
Research Articles on C-C Chemokine Receptor Type 7 (CCR7)
| Target | C-C Chemokine Receptor Type 7 (CCR7) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 11-37 amino acids from the N-terminal region of human CCR7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P32248 (UniProt, ExPASy) |
| UniProt Entry Name | CCR7_HUMAN |
| Gene Symbol | CCR7 |
| NCBI Accession | NP_001829.1 |
| KEGG | hsa:1236 |
| String | 9606.ENSP00000246657 |
| Molecular Weight | Calculated MW: 42.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |