Histone Deacetylase 5 (HDAC5) Antibody

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Catalogue No: abx005424
Price: US$348.00
(Size: 60 µl)

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Histone Deacetylase 5 (HDAC5) Antibody

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Datasheet SDS
HDAC5 Antibody is a Rabbit Polyclonal antibody against HDAC5. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Target Histone Deacetylase 5 (HDAC5)
Clonality Polyclonal
Reactivity Human
Tested Applications IF/ICC
Host Rabbit
Recommended dilutions IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide corresponding to human HDAC5
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9UQL6 (UniProt, ExPASy)
UniProt Secondary AC C9JFV9, O60340, O60528, Q96DY4
UniProt Entry Name HDAC5_HUMAN
Gene Symbol HDAC5
GeneID 10014
NCBI Accession NP_005465.2
String 9606.ENSP00000225983
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration 1 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Histone Deacetylase 5 (HDAC5)


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