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Syncytin-1 (HERV) Antibody
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Catalogue No: abx031651
Price:
US$326.25
(Size: 50 µl)
Orders to United States ship from United States
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Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. The protein, also known as syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. This protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
Research Articles on Syncytin-1 (HERV)
| Target | Syncytin-1 (HERV) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 400-429 amino acids from the Central region of human HERV (ERVWE1). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by Saturated Ammonium Sulfate (SAS) precipitation, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UQF0 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RPD4, O95244, O95245, Q8NHY7, Q9NRZ2, Q9NZG3 |
| UniProt Entry Name | SYCY1_HUMAN |
| GeneID | 30816 |
| NCBI Accession | NP_001124397.1 NP_055405.3 |
| String | 9606.ENSP00000419945 |
| Molecular Weight | Calculated MW: 59.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Concentration | 1.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |