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Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) Antibody
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Catalogue No: abx011752
Price:
US$427.75
(Size: 100 µl)
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The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates the kinases involved in the MAP kinase signaling pathway including MAPK7 and MAP2K4. This kinase has been shown to directly phosphorylate and activate I kappa B kinases (IKKs), and thus plays a role in NF- kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2 (PRKCL2/PRK2), which suggests its involvement in PRKCL2 regulated signaling process.
Research Articles on Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2)
| Target | Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human MAP3K2 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y2U5 (UniProt, ExPASy) |
| UniProt Secondary AC | B9EG87, Q53QL9, Q53S75, Q59GZ6, Q8NC32, Q9NYK3 |
| UniProt Entry Name | M3K2_HUMAN |
| Gene Symbol | MAP3K2 |
| GeneID | 10746 |
| OMIM | 609487 |
| HGNC | 6854 |
| Ensembl | ENSG00000169967 |
| String | 9606.ENSP00000387246 |
| Enzyme Commission Number | EC 2.7.11.25 |
| Molecular Weight | 70 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |