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Protein Tyrosine Phosphatase, Non Receptor Type 18 (PTPN18) Antibody
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Catalogue No: abx029158
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Research Articles on Protein Tyrosine Phosphatase, Non Receptor Type 18 (PTPN18)
| Target | Protein Tyrosine Phosphatase, Non Receptor Type 18 (PTPN18) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 430-459 amino acids from the C-terminal region of human PTPN18. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q99952 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E1E6, Q53P42 |
| UniProt Entry Name | PTN18_HUMAN |
| Gene Symbol | PTPN18 |
| KEGG | hsa:26469 |
| String | 9606.ENSP00000175756 |
| Molecular Weight | Calculated MW: 50.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse PTPN18. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |