Aryl Hydrocarbon Interacting Protein Like 1 (AIPL1) Antibody
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Catalogue No: abx004950
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US$217.50
(Size: 20 µl)
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Datasheet SDS
AIPL1 Antibody is a Rabbit Polyclonal antibody against AIPL1. Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5% of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20% of recessive LCA. Alternative splicing results in multiple transcript variants.
Research Articles on Aryl Hydrocarbon Interacting Protein Like 1 (AIPL1)
| Target | Aryl Hydrocarbon Interacting Protein Like 1 (AIPL1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to AIPL1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9NZN9 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DTM4, Q659W3, Q659W4, Q6ZZB6, Q8N6A0, Q9H873, Q9NS10 |
| UniProt Entry Name | AIPL1_HUMAN |
| Gene Symbol | AIPL1 |
| GeneID | 23746 |
| NCBI Accession | NP_055151.3 |
| String | 9606.ENSP00000370521 |
| Molecular Weight | Calculated MW: 44 kDa Observed MW: 40-45 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |