Aryl Hydrocarbon Interacting Protein Like 1 (AIPL1) Antibody

AIPL1 Antibody is a Rabbit Polyclonal antibody against AIPL1. Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5% of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20% of recessive LCA. Alternative splicing results in multiple transcript variants.

Target	Aryl Hydrocarbon Interacting Protein Like 1 (AIPL1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human AIPL1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NZN9 (UniProt, ExPASy)
UniProt Secondary AC	D3DTM4, Q659W3, Q659W4, Q6ZZB6, Q8N6A0, Q9H873, Q9NS10
UniProt Entry Name	AIPL1_HUMAN
Gene Symbol	AIPL1
GeneID	23746
NCBI Accession	NP_055151.3
String	9606.ENSP00000370521
Molecular Weight	Calculated MW: 44 kDa Observed MW: 40-45 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aryl Hydrocarbon Interacting Protein Like 1 (AIPL1)

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