Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) Antibody
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Catalogue No: abx029162
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.
Research Articles on Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11)
| Target | Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 605-632 amino acids from the Central region of human ARHGEF11. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O15085 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DVD0, Q5VY40, Q6PFW2 |
| UniProt Entry Name | ARHGB_HUMAN |
| Gene Symbol | ARHGEF11 |
| KEGG | hsa:9826 |
| String | 9606.ENSP00000357177 |
| Molecular Weight | Calculated MW: 168 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat ARHGEF11. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |