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CD63 Antigen (CD63) Antibody
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Catalogue No: abx032480
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US$326.25
(Size: 50 µl)
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Datasheet SDS
CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene.
Research Articles on CD63 Antigen (CD63)
| Target | CD63 Antigen (CD63) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/500, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 163-190 amino acids from the C-terminal region of human CD63. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P08962 (UniProt, ExPASy) |
| UniProt Secondary AC | F8VZE2, Q5TZP3, Q8N6Z9, Q9UCG6 |
| UniProt Entry Name | CD63_HUMAN |
| Gene Symbol | CD63 |
| GeneID | 967 |
| OMIM | 155740 |
| NCBI Accession | NP_001244318.1 NP_001244319.1 NP_001244320.1 NP_001244321.1 NP_001244329.1 NP_001244330.1 NP_001254627.1 NP_001771.1 |
| HGNC | 1692 |
| KEGG | hsa:967 |
| Ensembl | ENSG00000135404 |
| Molecular Weight | Calculated MW: 25.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |