Tetraspanin 30 / TSPAN30 (CD63) Antibody

CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene.

Target	Tetraspanin 30 / TSPAN30 (CD63)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/500, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 163-190 amino acids from the C-terminal region of human CD63.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P08962 (UniProt, ExPASy)
UniProt Secondary AC	F8VZE2, Q5TZP3, Q8N6Z9, Q9UCG6
NCBI Accession	NP_001244318.1 NP_001244319.1 NP_001244320.1 NP_001244321.1 NP_001244329.1 NP_001244330.1 NP_001254627.1 NP_001771.1
Molecular Weight	Calculated MW: 25.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tetraspanin 30 / TSPAN30 (CD63)

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