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Cluster of Differentiation 8 (CD8) Antibody
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Catalogue No: abx010529
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US$427.75
(Size: 100 µl)
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Datasheet SDS
CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds.It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine- protein kinase p56lck.
Research Articles on Cluster of Differentiation 8 (CD8)
| Target | Cluster of Differentiation 8 (CD8) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD8 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P01732 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DT80, D6W5M8, Q13970, Q4ZG17 |
| UniProt Entry Name | CD8A_HUMAN |
| Gene Symbol | CD8A |
| GeneID | 925 |
| OMIM | 186910 |
| HGNC | 1706 |
| KEGG | hsa:925 |
| Ensembl | ENSG00000153563 |
| String | 9606.ENSP00000386559 |
| Molecular Weight | 25 kDa |
| Buffer | PBS, containing 0.03% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |