Cluster of Differentiation 8 (CD8) Antibody

CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds.It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine- protein kinase p56lck.

Target	Cluster of Differentiation 8 (CD8)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human CD8 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01732 (UniProt, ExPASy)
UniProt Secondary AC	B4DT80, D6W5M8, Q13970, Q4ZG17
UniProt Entry Name	CD8A_HUMAN
Gene Symbol	CD8A
GeneID	925
OMIM	186910
HGNC	1706
KEGG	hsa:925
Ensembl	ENSG00000153563
String	9606.ENSP00000386559
Molecular Weight	25 kDa
Buffer	PBS, containing 0.03% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cluster of Differentiation 8 (CD8)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue