CFL1 (pS3) Antibody

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Catalogue No: abx000230
Price: US$232.00
(Size: 20 µl)

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Datasheet SDS
CFL1 (pS3) Antibody is a Rabbit Polyclonal antibody against CFL1 (pS3). The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Target CFL1 (pS3)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic phosphorylated peptide around S3 of human CFL1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P23528 (UniProt, ExPASy)
UniProt Secondary AC B3KUQ1, Q53Y87, Q9UCA2
UniProt Entry Name COF1_HUMAN
Gene Symbol CFL1
GeneID 1072
NCBI Accession NP_005498.1
KEGG hsa:1072
String 9606.ENSP00000432660
Molecular Weight Calculated MW: 19 kDa
Observed MW: 18 kDa
Buffer PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on CFL1 (pS3)


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