CFL1 (pS3) Antibody

CFL1 (pS3) Antibody is a Rabbit Polyclonal antibody against CFL1 (pS3). The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Target	CFL1 (pS3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around S3 of human CFL1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P23528 (UniProt, ExPASy)
UniProt Secondary AC	B3KUQ1, Q53Y87, Q9UCA2
UniProt Entry Name	COF1_HUMAN
Gene Symbol	CFL1
GeneID	1072
NCBI Accession	NP_005498.1
KEGG	hsa:1072
String	9606.ENSP00000432660
Molecular Weight	Calculated MW: 19 kDa Observed MW: 18 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on CFL1 (pS3)

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