CFL1 (pS3) Antibody

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Catalogue No: abx000230
Price: US$232.00
(Size: 20 µl)

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CFL1 (pS3) Antibody CFL1 (pS3) Antibody CFL1 (pS3) Antibody

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Datasheet SDS
CFL1 (pS3) Antibody is a Rabbit Polyclonal antibody against CFL1 (pS3). The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

Target CFL1 (pS3)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic peptide corresponding to CFL1 (pS3). The exact sequence is proprietary.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P23528 (UniProt, ExPASy)
UniProt Secondary AC B3KUQ1, Q53Y87, Q9UCA2
UniProt Entry Name COF1_HUMAN
Gene Symbol CFL1
GeneID 1072
NCBI Accession NP_005498.1
KEGG hsa:1072
String 9606.ENSP00000432660
Molecular Weight Calculated MW: 19 kDa
Observed MW: 18 kDa
Buffer PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on CFL1 (pS3)


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