Corticotropin Releasing Hormone (CRH) Antibody
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Catalogue No: abx001037
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US$348.00
(Size: 60 µl)
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Datasheet SDS
CRH Antibody is a Rabbit Polyclonal antibody against CRH. Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010].
Research Articles on Corticotropin Releasing Hormone (CRH)
| Target | Corticotropin Releasing Hormone (CRH) |
| Research Area | Neuroscience, Neuropeptides |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human CRH |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P06850 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KQS4 |
| UniProt Entry Name | CRF_HUMAN |
| Gene Symbol | CRH |
| GeneID | 1392 |
| NCBI Accession | NP_000747.1 |
| KEGG | hsa:1392 |
| String | 9606.ENSP00000276571 |
| Molecular Weight | Calculated MW: 21 kDa Observed MW: 35 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
