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Corticotropin Releasing Hormone (CRH) Antibody

Catalogue No: abx001037
Price: £120.00
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Corticotropin Releasing Hormone (CRH) Antibody

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CRH Antibody is a Rabbit Polyclonal antibody against CRH. Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010].

Target CRH
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CRH.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P06850 (UniProt, ExPASy)
UniProt Secondary AC B3KQS4
UniProt Entry Name CRF_HUMAN
Gene Symbol CRH
GeneID 1392
KEGG hsa:1392
String 9606.ENSP00000276571
Molecular Weight Calculated MW: 21 kDa
Observed MW: 35 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Corticotropin Releasing Hormone (CRH) Antibody

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