CREB Regulated Transcription Coactivator 3 (CRTC3) Antibody
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Catalogue No: abx015830
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation.Enhances the interaction of CREB1 with TAF4.Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR.Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells.Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).Tissue specificity: Predominantly expressed in B and T lymphocytes.Highest levels in lung.Also expressed in brain, colon, heart, kidney, ovary, and prostate.Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.
Research Articles on CREB Regulated Transcription Coactivator 3 (CRTC3)
| Target | CREB Regulated Transcription Coactivator 3 (CRTC3) |
| Research Area | Signal Transduction, Enzymes and Kinases, Apoptosis, Infection Immunity |
| Clonality | Monoclonal |
| Reactivity | Human, Monkey |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CRTC3 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| GeneID | 64784 |
| Molecular Weight | 68 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |