Cytochrome P450 3A4 (CYP3A4) Antibody
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Catalogue No: abx001982
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US$217.50
(Size: 20 µl)
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Datasheet SDS
CYP3A4 Antibody is a Rabbit Polyclonal antibody against CYP3A4. Cytochrome P450 3A(CYP3A) belongs to the cytochrome P450 family and the enzymes constitute an important detoxification system that contributes to primary metabolism of more than half of all prescribed medications.CYP3A expression determines impairment of drug absorption and efficient systemic clearance in a tissue-specific manner(PMID:17975676).This antibody is specific to CYP3A4.
Research Articles on Cytochrome P450 3A4 (CYP3A4)
| Target | Cytochrome P450 3A4 (CYP3A4) |
| Research Area | Metabolism |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/20 - 1/50, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to CYP3A4. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P08684 (UniProt, ExPASy) |
| UniProt Secondary AC | P05184, Q16757, Q9UK50 |
| UniProt Entry Name | CP3A4_HUMAN |
| Gene Symbol | CYP3A4 |
| GeneID | 1576 |
| OMIM | 124010 |
| NCBI Accession | NP_059488.2 |
| HGNC | 2637 |
| KEGG | hsa:1576 |
| Ensembl | ENSG00000160868 |
| String | 9606.ENSP00000337915 |
| Molecular Weight | Calculated MW: 57 kDa Observed MW: 50 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1.54 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
