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Cytochrome P450 3A4 (CYP3A4) Antibody
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Catalogue No: abx001982
Price:
£120.00
(Size: 20 µl)
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CYP3A4 Antibody is a Rabbit Polyclonal antibody against CYP3A4. Cytochrome P450 3A(CYP3A) belongs to the cytochrome P450 family and the enzymes constitute an important detoxification system that contributes to primary metabolism of more than half of all prescribed medications.CYP3A expression determines impairment of drug absorption and efficient systemic clearance in a tissue-specific manner(PMID:17975676).This antibody is specific to CYP3A4.
Research Articles on CYP3A4
| Target | CYP3A4 |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC: 1/20 - 1/50, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human CYP3A4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. |
| UniProt Primary AC | P08684 (UniProt, ExPASy) |
| UniProt Secondary AC | P05184, Q16757, Q9UK50 |
| UniProt Entry Name | CP3A4_HUMAN |
| Gene Symbol | CYP3A4 |
| GeneID | 1576 |
| OMIM | 124010 |
| HGNC | 2637 |
| KEGG | hsa:1576 |
| Ensembl | ENSG00000160868 |
| String | 9606.ENSP00000337915 |
| Molecular Weight | Calculated MW: 57 kDa Observed MW: 60 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide. |
| Concentration | 1.54 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
