Deleted In Azoospermia-Like (DAZL) Antibody
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Catalogue No: abx001030
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US$348.00
(Size: 60 µl)
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Datasheet SDS
DAZL Antibody is a Rabbit Polyclonal antibody against DAZL. The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
Research Articles on Deleted In Azoospermia-Like (DAZL)
| Target | Deleted In Azoospermia-Like (DAZL) |
| Clonality | Polyclonal |
| Reactivity | Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human DAZL |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q92904 (UniProt, ExPASy) |
| UniProt Secondary AC | O15396, Q5HYB4, Q92909 |
| UniProt Entry Name | DAZL_HUMAN |
| Gene Symbol | DAZL |
| GeneID | 1618 |
| NCBI Accession | NP_001342.2 |
| KEGG | hsa:1618 |
| String | 9606.ENSP00000250863 |
| Molecular Weight | Calculated MW: 33 kDa/35 kDa Observed MW: 38 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
