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Deleted In Azoospermia-Like (DAZL) Antibody

Catalogue No: abx001030
Price: £120.00
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Deleted In Azoospermia-Like (DAZL) Antibody

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DAZL Antibody is a Rabbit Polyclonal antibody against DAZL. The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

Target DAZL
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human DAZL.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q92904 (UniProt, ExPASy)
UniProt Secondary AC O15396, Q5HYB4, Q92909
UniProt Entry Name DAZL_HUMAN
Gene Symbol DAZL
GeneID 1618
KEGG hsa:1618
String 9606.ENSP00000250863
Molecular Weight Calculated MW: 33 kDa, 35 kDa
Observed MW: 33 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Deleted In Azoospermia-Like (DAZL) Antibody

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