Deleted In Azoospermia-Like (DAZL) Antibody

DAZL Antibody is a Rabbit Polyclonal antibody against DAZL. The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

Target	Deleted In Azoospermia-Like (DAZL)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 186-295 of human DAZL.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92904 (UniProt, ExPASy)
UniProt Secondary AC	O15396, Q5HYB4, Q92909
UniProt Entry Name	DAZL_HUMAN
Gene Symbol	DAZL
GeneID	1618
NCBI Accession	NP_001342.2
KEGG	hsa:1618
String	9606.ENSP00000250863
Molecular Weight	Calculated MW: 33 kDa Observed MW: 33 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Deleted In Azoospermia-Like (DAZL)

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