+44 (0) 1223 755950
+1 832 327 7413
Eukaryotic Translation Initiation Factor 5A-1 (EIF5A) Antibody
REQUEST MORE INFO
Catalogue No: abx001637
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
EIF5A Antibody is a Rabbit Polyclonal antibody against EIF5A. mRNA-binding protein involved in translation elongation. Has an important function at the level of Mrna turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
Research Articles on Eukaryotic Translation Initiation Factor 5A-1 (EIF5A)
| Target | Eukaryotic Translation Initiation Factor 5A-1 (EIF5A) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human EIF5A |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P63241 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K9A0, D3DTP2, P10159, Q16182, Q7L7L3, Q7Z4L1, Q9D0G2 |
| UniProt Entry Name | IF5A1_HUMAN |
| Gene Symbol | EIF5A |
| GeneID | 1984 |
| NCBI Accession | NP_001137234.1 |
| KEGG | hsa:1984 |
| String | 9606.ENSP00000336702 |
| Molecular Weight | Calculated MW: 16 kDa/20 kDa Observed MW: 17 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
