Eukaryotic Translation Initiation Factor 5A-1 (EIF5A) Antibody

EIF5A Antibody is a Rabbit Polyclonal antibody against EIF5A. mRNA-binding protein involved in translation elongation. Has an important function at the level of Mrna turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

Target	Eukaryotic Translation Initiation Factor 5A-1 (EIF5A)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human eIF5A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P63241 (UniProt, ExPASy)
UniProt Secondary AC	A8K9A0, D3DTP2, P10159, Q16182, Q7L7L3, Q7Z4L1, Q9D0G2
UniProt Entry Name	IF5A1_HUMAN
Gene Symbol	EIF5A
GeneID	1984
NCBI Accession	NP_001137234.1
KEGG	hsa:1984
String	9606.ENSP00000336702
Molecular Weight	Calculated MW: 17 kDa Observed MW: 17 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Eukaryotic Translation Initiation Factor 5A-1 (EIF5A)

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