Eukaryotic Translation Initiation Factor 5A-1 (EIF5A) Antibody

Catalogue No: abx001637
Price: £120.00
(Size: 20 µl)

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Datasheet SDS
EIF5A Antibody is a Rabbit Polyclonal antibody against EIF5A. mRNA-binding protein involved in translation elongation. Has an important function at the level of Mrna turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

Target EIF5A
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human EIF5A.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P63241 (UniProt, ExPASy)
UniProt Secondary AC A8K9A0, D3DTP2, P10159, Q16182, Q7L7L3, Q7Z4L1, Q9D0G2
UniProt Entry Name IF5A1_HUMAN
Gene Symbol EIF5A
GeneID 1984
KEGG hsa:1984
String 9606.ENSP00000336702
Molecular Weight Calculated MW: 16 kDa, 20 kDa
Observed MW: 17 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on EIF5A

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