G Protein Pathway Suppressor 2 (GPS2) Antibody
REQUEST MORE INFO
Catalogue No: abx002842
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
GPS2 Antibody is a Rabbit Polyclonal antibody against GPS2. This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
Research Articles on G Protein Pathway Suppressor 2 (GPS2)
| Target | G Protein Pathway Suppressor 2 (GPS2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IP: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to mouse GPS2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q13227 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DXA1, Q6FHM8 |
| UniProt Entry Name | GPS2_HUMAN |
| Gene Symbol | GPS2 |
| GeneID | 2874 |
| NCBI Accession | NP_062700.2 |
| KEGG | hsa:2874 |
| String | 9606.ENSP00000370104 |
| Molecular Weight | Calculated MW: 20 kDa Observed MW: 37 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
