G Protein Pathway Suppressor 2 (GPS2) Antibody

Catalogue No: abx002842
Price: £120.00
(Size: 20 µl)
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GPS2 Antibody is a Rabbit Polyclonal antibody against GPS2. This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

Target GPS2
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IP: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human GPS2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13227 (UniProt, ExPASy)
UniProt Secondary AC B4DXA1, Q6FHM8
UniProt Entry Name GPS2_HUMAN
Gene Symbol GPS2
GeneID 2874
KEGG hsa:2874
String 9606.ENSP00000370104
Molecular Weight Calculated MW: 20 kDa
Observed MW: 37 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on G Protein Pathway Suppressor 2 (GPS2) Antibody

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