G Protein Pathway Suppressor 2 (GPS2) Antibody

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Catalogue No: abx002842
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
GPS2 Antibody is a Rabbit Polyclonal antibody against GPS2. This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

Target G Protein Pathway Suppressor 2 (GPS2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of mouse GPS2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13227 (UniProt, ExPASy)
UniProt Secondary AC B4DXA1, Q6FHM8
UniProt Entry Name GPS2_HUMAN
Gene Symbol GPS2
GeneID 2874
NCBI Accession NP_062700.2
KEGG hsa:2874
String 9606.ENSP00000370104
Molecular Weight Calculated MW: 20 kDa
Observed MW: 37 kDa
Buffer PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on G Protein Pathway Suppressor 2 (GPS2)


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