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Hexokinase-1 (HK1) Antibody
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Catalogue No: abx015885
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate.Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK).Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids.Glucokinase lacks the N-terminal hydrophobic cluster.The hydrophobic cluster is thought to be necessary for membrane binding.This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases.HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.
Research Articles on Hexokinase-1 (HK1)
| Target | Hexokinase-1 (HK1) |
| Research Area | Enzymes and Kinases, Metabolism |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human HK1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P19367 (UniProt, ExPASy) |
| UniProt Entry Name | HXK1_HUMAN |
| GeneID | 3098 |
| KEGG | hsa:3098 |
| String | 9606.ENSP00000402103 |
| Molecular Weight | 120 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |