Junction Plakoglobin (JUP) Antibody
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Catalogue No: abx000917
Price:
US$217.50
(Size: 20 µl)
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Datasheet SDS
JUP Antibody is a Rabbit Polyclonal antibody against JUP. This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008].
Research Articles on Junction Plakoglobin (JUP)
| Target | Junction Plakoglobin (JUP) |
| Research Area | Cellular Differentiation and Adhesion |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to JUP. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P14923 (UniProt, ExPASy) |
| UniProt Secondary AC | Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9 |
| UniProt Entry Name | PLAK_HUMAN |
| Gene Symbol | JUP |
| GeneID | 3728 |
| OMIM | 173325 |
| NCBI Accession | NP_002221.1 |
| HGNC | 6207 |
| KEGG | hsa:3728 |
| Ensembl | ENSG00000173801 |
| String | 9606.ENSP00000377508 |
| Molecular Weight | Calculated MW: 82 kDa Observed MW: 82 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |