MAP Kinase-Activated Protein Kinase 2 Phospho-Thr334 (MAPKAPK2 pT334) Antibody
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Catalogue No: abx031874
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
Research Articles on MAP Kinase-Activated Protein Kinase 2 Phospho-Thr334 (MAPKAPK2 pT334)
| Target | MAP Kinase-Activated Protein Kinase 2 Phospho-Thr334 (MAPKAPK2 pT334) |
| Clonality | Polyclonal |
| Target Modification | Ser272 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, DB |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/100, DB: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S272 of human MAPKAPK2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P49137 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5SY30, Q5SY41, Q8IYD6 |
| UniProt Entry Name | MAPK2_HUMAN |
| KEGG | hsa:9261 |
| String | 9606.ENSP00000356070 |
| Molecular Weight | Calculated MW: 45.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rabbit MAPKAPK2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |