MAP Kinase-Activated Protein Kinase 2 Phospho-Thr334 (MAPKAPK2 pT334) Antibody

This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

Target	MAP Kinase-Activated Protein Kinase 2 Phospho-Thr334 (MAPKAPK2 pT334)
Clonality	Polyclonal
Target Modification	Ser272
Modification	Phosphorylation
Reactivity	Human
Tested Applications	ELISA, IHC, DB
Host	Rabbit
Recommended dilutions	IHC-P: 1/50 - 1/100, DB: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S272 of human MAPKAPK2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49137 (UniProt, ExPASy)
UniProt Secondary AC	Q5SY30, Q5SY41, Q8IYD6
UniProt Entry Name	MAPK2_HUMAN
KEGG	hsa:9261
String	9606.ENSP00000356070
Molecular Weight	Calculated MW: 45.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rabbit MAPKAPK2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on MAP Kinase-Activated Protein Kinase 2 Phospho-Thr334 (MAPKAPK2 pT334)

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