Programmed Cell Death Protein 1 (PDCD1) Antibody
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Catalogue No: abx004272
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US$377.00
(Size: 60 µl)
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Datasheet SDS
PDCD1 Antibody is a Rabbit Polyclonal antibody against PDCD1. This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Research Articles on Programmed Cell Death Protein 1 (PDCD1)
| Target | Programmed Cell Death Protein 1 (PDCD1) |
| Research Area | Apoptosis, Immunology, Endocrinology, Autoimmunity |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human PD-1/CD279 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q15116 (UniProt, ExPASy) |
| UniProt Secondary AC | O00517, Q8IX89 |
| UniProt Entry Name | PDCD1_HUMAN |
| Gene Symbol | PDCD1 |
| GeneID | 5133 |
| OMIM | 600244 |
| NCBI Accession | NP_005009.2 |
| KEGG | hsa:5133 |
| String | 9606.ENSP00000335062 |
| Molecular Weight | Calculated MW: 31 kDa Observed MW: 35 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
