Programmed Cell Death Protein 1 (PDCD1) Antibody

PDCD1 Antibody is a Rabbit Polyclonal antibody against PDCD1. This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Target	Programmed Cell Death Protein 1 (PDCD1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 21-170 of human PD-1/CD279.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15116 (UniProt, ExPASy)
UniProt Secondary AC	O00517, Q8IX89
UniProt Entry Name	PDCD1_HUMAN
Gene Symbol	PDCD1
GeneID	5133
OMIM	600244
NCBI Accession	NP_005009.2
KEGG	hsa:5133
String	9606.ENSP00000335062
Molecular Weight	Calculated MW: 32 kDa Observed MW: 35 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Programmed Cell Death Protein 1 (PDCD1)

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