26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) Antibody
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Catalogue No: abx014069
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(Size: 10 µg)
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Datasheet SDS
Rabbit polyclonal antibody against 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) protein. Immunogen region is Internal. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11)
| Target | 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/3000, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | The antiserum was produced against synthesized peptide derived from internal of human PSMD11. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O00231 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K3I7, E1P663, O00495, Q53FT5 |
| UniProt Entry Name | PSD11_HUMAN |
| Gene Symbol | PSMD11 |
| GeneID | 5717 |
| OMIM | 604449 |
| NCBI Accession | NP_001257411.1 NM_001270482.1 |
| HGNC | 9556 |
| KEGG | hsa:5717 |
| Ensembl | ENSG00000108671 |
| String | 9606.ENSP00000261712 |
| Buffer | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |