26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) Antibody

Rabbit polyclonal antibody against 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) protein. Immunogen region is Internal. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene.

Target	26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/3000, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	The antiserum was produced against synthesized peptide derived from internal of human PSMD11.
Isotype	IgG
Form	Liquid
Purification	Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00231 (UniProt, ExPASy)
UniProt Secondary AC	A8K3I7, E1P663, O00495, Q53FT5
UniProt Entry Name	PSD11_HUMAN
Gene Symbol	PSMD11
GeneID	5717
OMIM	604449
NCBI Accession	NP_001257411.1 NM_001270482.1
HGNC	9556
KEGG	hsa:5717
Ensembl	ENSG00000108671
String	9606.ENSP00000261712
Buffer	PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11)

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