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Poly(U) Binding Splicing Factor 60 (PUF60) Antibody
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Catalogue No: abx005146
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US$217.50
(Size: 20 µl)
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Datasheet SDS
PUF60 Antibody is a Rabbit Polyclonal antibody against PUF60. This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Research Articles on Poly(U) Binding Splicing Factor 60 (PUF60)
| Target | Poly(U) Binding Splicing Factor 60 (PUF60) |
| Research Area | Immunology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to PUF60. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9UHX1 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K8K8, Q969E7, Q96D94, Q96H63, Q99628, Q9NZA0, Q9UJY7 |
| UniProt Entry Name | PUF60_HUMAN |
| Gene Symbol | PUF60 |
| GeneID | 22827 |
| NCBI Accession | NP_055096.2 |
| String | 9606.ENSP00000434359 |
| Molecular Weight | Calculated MW: 60 kDa Observed MW: 65 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |