Poly(U) Binding Splicing Factor 60 (PUF60) Antibody

PUF60 Antibody is a Rabbit Polyclonal antibody against PUF60. This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Target	Poly(U) Binding Splicing Factor 60 (PUF60)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 243-542 of human PUF60.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UHX1 (UniProt, ExPASy)
UniProt Secondary AC	A8K8K8, Q969E7, Q96D94, Q96H63, Q99628, Q9NZA0, Q9UJY7
UniProt Entry Name	PUF60_HUMAN
Gene Symbol	PUF60
GeneID	22827
NCBI Accession	NP_055096.2
String	9606.ENSP00000434359
Molecular Weight	Calculated MW: 60 kDa Observed MW: 65 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Poly(U) Binding Splicing Factor 60 (PUF60)

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