Sphingosine Kinase 1 (SPHK1) Antibody

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Catalogue No: abx000568
Price: US$217.50
(Size: 20 µl)

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Western blot analysis of various lysates using SPHK1 Antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Sphingosine Kinase 1 (SPHK1) Antibody

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Datasheet SDS
SPHK1 Antibody is a Rabbit Polyclonal antibody against SPHK1. The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target Sphingosine Kinase 1 (SPHK1)
Research Area Enzymes and Kinases
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein corresponding to SPHK1. The exact sequence is proprietary.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Shelf Life 12 months.
UniProt Primary AC Q9NYA1 (UniProt, ExPASy)
UniProt Secondary AC Q8N632, Q96GK1, Q9HD92, Q9NY70, Q9NYL3
Gene Symbol SPHK1
GeneID 8877
NCBI Accession NP_001136074.1
Molecular Weight Calculated MW: 43 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Sphingosine Kinase 1 (SPHK1)


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