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Sphingosine Kinase 1 (SPHK1) Antibody

Catalogue No: abx000568
Price: £120.00
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Sphingosine Kinase 1 (SPHK1) Antibody Sphingosine Kinase 1 (SPHK1) Antibody Sphingosine Kinase 1 (SPHK1) Antibody Sphingosine Kinase 1 (SPHK1) Antibody

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SPHK1 Antibody is a Rabbit Polyclonal antibody against SPHK1. The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target SPHK1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human SPHK1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9NYA1 (UniProt, ExPASy)
UniProt Secondary AC Q8N632, Q96GK1, Q9HD92, Q9NY70, Q9NYL3
Gene Symbol SPHK1
GeneID 8877
Molecular Weight Calculated MW: 42 kDa, 43 kDa, 51 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Sphingosine Kinase 1 (SPHK1) Antibody

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