Sphingosine Kinase 1 (SPHK1) Antibody

Catalogue No: abx000568
Price: £95.00
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Sphingosine Kinase 1 (SPHK1) Antibody Sphingosine Kinase 1 (SPHK1) Antibody Sphingosine Kinase 1 (SPHK1) Antibody Sphingosine Kinase 1 (SPHK1) Antibody

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SPHK1 Antibody is a Rabbit Polyclonal antibody against SPHK1. The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target SPHK1
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein of human SPHK1.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 42 kDa/43 kDa/51 kDa
Observed MW: 55 kDa
Swiss Prot Q9NYA1
GeneID 8877
Gene Symbol SPHK1
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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