TGF-Beta-Activated Kinase 1 And MAP3K7-Binding Protein 2 (TAB2) Antibody
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Catalogue No: abx011864
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappa B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Research Articles on TGF-Beta-Activated Kinase 1 And MAP3K7-Binding Protein 2 (TAB2)
| Target | TGF-Beta-Activated Kinase 1 And MAP3K7-Binding Protein 2 (TAB2) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human TAB2 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9NYJ8 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RCC4, E1P5A0, O94838, Q6I9W8, Q76N06, Q9UFP7 |
| UniProt Entry Name | TAB2_HUMAN |
| Gene Symbol | TAB2 |
| GeneID | 23118 |
| OMIM | 605101 |
| HGNC | 17075 |
| Ensembl | ENSG00000055208 |
| String | 9606.ENSP00000356426 |
| Molecular Weight | 80 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |