Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) Antibody
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Catalogue No: abx001051
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US$348.00
(Size: 60 µl)
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Datasheet SDS
TNFRSF10C Antibody is a Rabbit Polyclonal antibody against TNFRSF10C. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C)
| Target | Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) |
| Research Area | Cellular Differentiation and Adhesion, Apoptosis |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human TNFRSF10C |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O14798 (UniProt, ExPASy) |
| UniProt Secondary AC | O14755, Q08AS6, Q6FH98, Q6UXM5 |
| UniProt Entry Name | TR10C_HUMAN |
| Gene Symbol | TNFRSF10C |
| GeneID | 8794 |
| NCBI Accession | NP_003832.2 |
| KEGG | hsa:8794 |
| String | 9606.ENSP00000349324 |
| Molecular Weight | Calculated MW: 27 kDa Observed MW: 27 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
