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Serine/threonine-Protein Kinase VRK1 (VRK1) Antibody
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Catalogue No: abx034922
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US$623.50
(Size: 100 µl)
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Datasheet SDS
Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. This antibody is supplied as crude ascites.
Research Articles on Serine/threonine-Protein Kinase VRK1 (VRK1)
| Target | Serine/threonine-Protein Kinase VRK1 (VRK1) |
| Research Area | Enzymes and Kinases |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified His-tagged Human VRK1 protein |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q99986 (UniProt, ExPASy) |
| UniProt Secondary AC | Q3SYL2 |
| UniProt Entry Name | VRK1_HUMAN |
| NCBI Accession | NP_003375.1 |
| KEGG | hsa:7443 |
| String | 9606.ENSP00000216639 |
| Molecular Weight | Calculated MW: 45.5 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |