beta 2 Adrenergic Receptor Antibody

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This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V) 1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

Target	beta 2 Adrenergic Receptor
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human beta 2 Adrenergic Receptor (BAR2).
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P07550 (UniProt, ExPASy)
UniProt Entry Name	ADRB2_HUMAN
NCBI Accession	NP_000015.1
KEGG	hsa:154
String	9606.ENSP00000305372
Molecular Weight	Calculated MW: 46.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Please enquire.
Note	This product is for research use only.

Research Articles on beta 2 Adrenergic Receptor

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