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Autoimmune Regulator (AIRE) Antibody

Catalogue No: abx001466
Price: £120.00
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Autoimmune Regulator (AIRE) Antibody Autoimmune Regulator (AIRE) Antibody

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AIRE Antibody is a Rabbit Polyclonal antibody against AIRE. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012].

Target AIRE
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human AIRE.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O43918 (UniProt, ExPASy)
UniProt Secondary AC B2RP50, O43922, O43932, O75745
UniProt Entry Name AIRE_HUMAN
Gene Symbol AIRE
GeneID 326
KEGG hsa:326
String 9606.ENSP00000291582
Molecular Weight Calculated MW: 25 kDa, 35 kDa, 36 kDa, 57 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Autoimmune Regulator (AIRE) Antibody

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