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RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) Antibody

Catalogue No: abx000095
Price: £120.00
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RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) Antibody

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AKT2 (pS474) Antibody is a Rabbit Polyclonal antibody against AKT2 (pS474). This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Target RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474)
Clonality Polyclonal
Target Modification Ser474
Modification Phosphorylation
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S474 of human AKT2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P31751 (UniProt, ExPASy)
UniProt Secondary AC B2RBD8, Q05BV0, Q0VAN0, Q0VAN1, Q68GC0
UniProt Entry Name AKT2_HUMAN
Gene Symbol AKT2
GeneID 208
KEGG hsa:208
String 9606.ENSP00000375892
Molecular Weight Calculated MW: 51 kDa, 55 kDa
Observed MW: 56 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) Antibody

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