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Hydroperoxide Isomerase ALOXE3 (ALOXE3) Antibody
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Catalogue No: abx025721
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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ALOXE3 is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R, 12R-epoxyeicosa-5Z, 9E, 14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin.
Research Articles on Hydroperoxide Isomerase ALOXE3 (ALOXE3)
| Target | Hydroperoxide Isomerase ALOXE3 (ALOXE3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 223-252 amino acids from the Central region of human ALOXE3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9BYJ1 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R981, B7Z3W0, Q3ZB74, Q9H4F2, Q9HC22 |
| UniProt Entry Name | LOXE3_HUMAN |
| Gene Symbol | ALOXE3 |
| String | 9606.ENSP00000314879 |
| Molecular Weight | Calculated MW: 80.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |